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Article

IL ‐4 drastically decreases deuterosomal and multiciliated cells via alteration in progenitor cell differentiation

8 Mar 2023

Abstract excerpt

BACKGROUND: Allergic inflammation affects the epithelial cell populations resulting in goblet cell hyperplasia and decreased ciliated cells. Recent advances in single-cell RNA sequencing (scRNAseq) have enabled the identification of new cell subtypes and genomic features of single cells. In this study, we aimed to investigate the effect of allergic inflammation in nasal epithelial cell transcriptomes at the...

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PMID: 36883528
DOI: 10.1111/all.15705

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