Development of PCR-based genetic test for detection of TTF1 mutation causing abortion in Holstein Friesian cattle.

doi:10.1111/rda.14581

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Development of PCR-based genetic test for detection of TTF1 mutation causing abortion in Holstein Friesian cattle.

Reproduction in domestic animals = Zuchthygiene - 1 May 2024

Surati Utsav, Niranjan Saket Kumar

Abstract excerpt

A stop-gain mutation (rs715966442; BTA11: 1,02,463,944 nucleotide position) in transcription termination factor, RNA polymerase I (TTF1) gene causes abortion in Holstein Friesian (HF) cattle. A PCR-restriction fragment length polymorphism (PCR-RFLP)-based genetic test has been developed and validated to screen the TTF1 mutation locus in HF cattle. The mutation locus was screened in 80 HF and HF crossbreds using...

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PMID: 38698693
DOI: 10.1111/rda.14581

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