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Article

Identification of a mutation associated with factor XI deficiency in Holstein cattle.

Animal genetics - 1 Dec 2004

Marron B M, Robinson J L, Gentry P A, Beever J E

Abstract excerpt

An autosomal recessive deficiency of blood coagulation factor XI (FXI) has been described in Holstein cattle. Current testing methods are unsuitable for accurately identifying carriers (heterozygotes) of the disease. To identify the molecular basis of this deficiency, a polymerase chain reaction (PCR)-based strategy was implemented to clone and sequence the bovine FXI gene (F11) from animals of different...

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PMID: 15566468
DOI: 10.1111/j.1365-2052.2004.01202.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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