Article
Antigen presentation plays positive roles in the regenerative response to cardiac injury in zebrafish.
Nature communications - 29 Apr 2024
Cardeira-da-Silva João, Wang Qianchen, Sagvekar Pooja, Mintcheva Janita, Latting Stephan, Günther Stefan, Ramadass Radhan, Yekelchyk Michail, Preussner Jens, Looso Mario, Junker Jan Philipp, Stainier Didier Y R
Abstract excerpt
In contrast to adult mammals, adult zebrafish can fully regenerate injured cardiac tissue, and this regeneration process requires an adequate and tightly controlled immune response. However, which components of the immune response are required during regeneration is unclear. Here, we report positive roles for the antigen presentation-adaptive immunity axis during zebrafish cardiac regeneration. We find that...
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