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Article

Identification and Quantification of (t)RNA Modifications in Pseudomonas aeruginosa by Liquid Chromatography–Tandem Mass Spectrometry

15 Jan 2019

Abstract excerpt

Transfer RNA (tRNA) modifications impact the structure and function of tRNAs, thus affecting the efficiency and fidelity of translation. In the opportunistic pathogen Pseudomonas aeruginosa translational regulation plays an important but less defined role in adaptation to changing environments. In this study, we have explored tRNA modifications in P. aeruginosa through LC-MS/MS approaches. Neutral loss scanning...

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PMID: 30644616
DOI: 10.1002/cbic.201800741

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