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Article

APOE ε2-Carriers Are Associated with an Increased Risk of Primary Angle-Closure Glaucoma in Patients of Saudi Origin.

International journal of molecular sciences - 22 Apr 2024

Kondkar Altaf A, Azad Taif A, Sultan Tahira, Khatlani Tanvir, Alshehri Abdulaziz A, Radhakrishnan Rakesh, Lobo Glenn P, Alsirhy Ehab, Almobarak Faisal A, Osman Essam A, Al-Obeidan Saleh A

Abstract excerpt

This study investigated the association between apolipoprotein E (APOE) gene polymorphisms (rs429358 and rs7412) and primary angle-closure glaucoma (PACG) and pseudoexfoliation glaucoma (PXG) in a Saudi cohort. Genotyping of 437 DNA samples (251 controls, 92 PACG, 94 PXG) was conducted using PCR-based Sanger sequencing. The results showed no significant differences in the allele and genotype frequencies of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38674156
DOI: 10.3390/ijms25084571
PMCID: PMC11050284

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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