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Article

Apolipoprotein E genotypes in pseudoexfoliation syndrome and pseudoexfoliation glaucoma.

Journal of glaucoma - 1 Jan 2000

Krumbiegel Mandy, Pasutto Francesca, Mardin Christian Y, Weisschuh Nicole, Paoli Daniela, Gramer Eugen, Weber Bernhard H F, Kruse Friedrich E, Schlötzer-Schrehardt Ursula, Reis André

Abstract excerpt

PURPOSE: Pseudoexfoliation (PEX) syndrome, an age-related, systemic, elastic microfibrillopathy, is characterized by fibrillar-granular deposits in the anterior segment of the eye. Although not representing a true amyloidosis, PEX syndrome shares some features with amyloid disorders, such as Alzheimer disease. It has been shown that amyloid-associated proteins also occur in association with PEX fibrils....

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Identifiers

PMID: 20543710
DOI: 10.1097/IJG.0b013e3181ca76c4

Genes

APOE

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Exploring functional candidate genes for genetic association in german patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma.Semantic proximity Read ↗

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Genetic variants and haplotypes in fibulin-5 (FBLN5) are associated with pseudoexfoliation glaucoma but not with pseudoexfoliation syndrome.Semantic proximity Read ↗

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