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Article

Using Portuguese BRCA pathogenic variation as a model to study the impact of human admixture on human health.

BMC genomics - 27 Apr 2024

Andaluz Stephanie, Zhao Bojin, Sinha Siddharth, Lagniton Philip Naderev Panuringan, Costa Diogo Alpuim, Ding Xiaofan, Brito Miguel, Wang San Ming

Abstract excerpt

BACKGROUND: Admixture occurs between different ethnic human populations. The global colonization in recent centuries by Europeans led to the most significant admixture in human history. While admixture may enhance genetic diversity for better fitness, it may also impact on human health by transmitting genetic variants for disease susceptibility in the admixture population. The admixture by Portuguese global...

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Identifiers

PMID: 38671360
DOI: 10.1186/s12864-024-10311-4
PMCID: PMC11055274

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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