Article
Impact of Prospero Homeobox-1 (PROX-1) οn the Oncogenic Phenotypes of Hepatocellular Carcinoma Cells.
Cancer genomics & proteomics - 1 Jan 2000
Hong Ji-Yun, Park Sun-Young, Park Young-Lan, You Ga-Ram, Yoon Jae Hyun, Joo Young-Eun, Choi Sung Kyu, Cho Sung-Bum
Abstract excerpt
BACKGROUND/AIM: Transcriptional factor prospero homeobox-1 (PROX-1) is crucial for the embryonic development of various organs and cell fate specification. It exhibits either an oncogenic or tumor suppressive activity depending on cancer types. However, the relationship between PROX-1 and hepatocellular carcinoma (HCC) remains obscure. This study was conducted to investigate the effect of PROX-1 on the invasive...
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