Article
Small interfering RNA-directed targeting of RON alters invasive and oncogenic phenotypes of human hepatocellular carcinoma cells.
Oncology reports - 1 Dec 2011
Cho Sung-Bum, Park Young-Lan, Song Young-A, Kim Kyu-Yeol, Lee Gi-Hoon, Cho Dae-Ho, Myung Dae-Seong, Park Kang-Jin, Lee Wan-Sik, Chung Ik-Joo, Choi Sung-Kyu, Kim Kyung-Keun, Joo Young-Eun
Abstract excerpt
The recepteur d'origine nantais (RON) receptor tyrosine kinase is highly expressed in various cancers including human hepatocellular carcinoma (HCC) and involved in tumor progression. The aims of the current study were to evaluate whether RON affects tumor cell behavior and oncogenic signaling cascades in HCC cells. We investigated the biologic role of RON on tumor...
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