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Spatiotemporally resolved colorectal oncogenesis in mini-colons ex vivo

24 Apr 2024

Abstract excerpt

Abstract Three-dimensional organoid culture technologies have revolutionized cancer research by allowing for more realistic and scalable reproductions of both tumour and microenvironmental structures 1–3 . This has enabled better modelling of low-complexity cancer cell behaviours that occur over relatively short periods of time 4 . However, available organoid systems do not capture the intricate evolutionary...

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PMID: 38658753
DOI: 10.1038/s41586-024-07330-2

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