Prevalence of the protective OAS1 rs10774671-G allele against severe COVID-19 in Moroccans: implications for a North African Neanderthal connection.

doi:10.1007/s00705-024-06038-y

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Prevalence of the protective OAS1 rs10774671-G allele against severe COVID-19 in Moroccans: implications for a North African Neanderthal connection.

Archives of virology - 25 Apr 2024

Yousfi Fatima Zahra El, Haroun Abbas Ermilo, Nebhani Chaimae, Belayachi Jihane, Askander Omar, Fahime Elmostafa El, Fares Hakima, Ennibi Khalid, Abouqal Redouane, Razine Rachid, Bouhouche Ahmed

Abstract excerpt

The clinical presentation of COVID-19 shows high variability among individuals, which is partly due to genetic factors. The OAS1/2/3 cluster has been found to be strongly associated with COVID-19 severity. We examined this locus in the Moroccan population for the occurrence of the critical variant rs10774671 and its respective haplotype blocks. The frequency of single-nucleotide polymorphisms (SNPs) in the...

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PMID: 38658463
DOI: 10.1007/s00705-024-06038-y
PMCID: PMC11043147

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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