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Article

Warburg Effect Reshapes Tumor Immunogenicity.

Cancer research - 2 Jul 2024

Enríquez José A, Mittelbrunn María

Abstract excerpt

Tumor cells rewire their metabolism to fulfill the demands of highly proliferative cells. This changes cellular metabolism to adapt to fuel and oxygen availability for energy production and to increase the synthesis capacity of building blocks for cell division and growth. In addition, the metabolic shift modulates the immunogenicity of the tumor cells. Recently, Mahmood and colleagues reported a connection...

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PMID: 38657107
DOI: 10.1158/0008-5472.CAN-24-1304

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