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BCAT1 , IKZF1 and SEPT9 : methylated DNA biomarkers for detection of pan-gastrointestinal adenocarcinomas

22 Apr 2024

Abstract excerpt

Introduction Methylated circulating tumour DNA (ctDNA) blood tests for BCAT1/IKZF1 (COLVERA) and SEPT9 (Epi proColon) are used to detect colorectal cancer (CRC). However, there are no ctDNA assays approved for other gastrointestinal adenocarcinomas. We aimed to characterize BCAT1, IKZF1 and SEPT9 methylation in different gastrointestinal adenocarcinoma and non-gastrointestinal tumours to determine if these...

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PMID: 38644767
DOI: 10.1080/1354750x.2024.2340663

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