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Article

Circulating Methylated SEPT9 DNA in Plasma Is a Biomarker for Colorectal Cancer

1 May 2009

Abstract excerpt

BACKGROUND: The presence of aberrantly methylated SEPT9 DNA in plasma is highly correlated with the occurrence of colorectal cancer. We report the development of a new SEPT9 biomarker assay and its validation in case-control studies. The development of such a minimally invasive blood-based test may help to reduce the current gap in screening coverage. METHODS: A new SEPT9 DNA methylation assay was developed for...

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PMID: 19406918
DOI: 10.1373/clinchem.2008.115808

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