Article
Sofosbuvir-velpatasvir in children 3-17 years old with hepatitis C virus infection.
Journal of pediatric gastroenterology and nutrition - 1 Jun 2024
Jonas Maureen M, Romero Rene, Rosenthal Philip, Lin Chuan-Hao, Verucchi Gabriella, Wen Jessica, Balistreri William F, Whitworth Suzanne, Bansal Sanjay, Leung Daniel H, Narkewicz Michael R, Gonzalez-Peralta Regino P, Mangia Alessandra, Karnsakul Wikrom, Rao Girish S, Shao Jiang, de Jong Jan, Parhy Bandita, Osinusi Anu, Kersey Kathryn, Murray Karen F, Sokal Etienne M, Schwarz Kathleen B
Abstract excerpt
BACKGROUND: The safety and efficacy of sofosbuvir-velpatasvir in children aged 3-17 years with chronic hepatitis C virus (HCV) infection of any genotype were evaluated. METHODS: In this Phase 2, multicenter, open-label study, patients received once daily for 12 weeks either sofosbuvir-velpatasvir 400/100 mg tablet (12-17 years), 200/50 mg low dose tablet or oral granules (3-11 years and ≥17 kg), or 150/37.5 mg...
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