Article
Hepatitis C Virus in Children: Deferring Treatment in Expectation of Direct-Acting Antiviral Agents.
The Israel Medical Association journal : IMAJ - 1 Nov 2015
Granot Esther, Sokal Etienne M
Abstract excerpt
The major route of hepatitis C virus (HCV) infection in the pediatric age group is vertical, with infection occurring in up to 5% of infants born to mothers positive for HCV-RNA. The natural course of pediatric HCV infection is characterized by a high rate of spontaneous clearance, an asymptomatic clinical course, and normal or mild histologic changes. Cirrhosis is reported in 1-2% of children, and progression to...
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