Article
Pharmacokinetic evaluation of sofosbuvir/velpatasvir for the treatment of Chronic Hepatitis C in pediatrics aged 3 and older.
Expert opinion on drug metabolism & toxicology - 1 Dec 2023
Tuan Jessica, Okoli Adaora, Ogbuagu Onyema
Abstract excerpt
INTRODUCTION: The World Health Organization proposed targets to eliminate hepatitis C virus (HCV) by 2030, aiming to treat ≥80% of people with HCV, decreasing new chronic infections by 90% and liver-related mortality by 65%. While children/adolescents represent a minority of cases, the true burden is underestimated. Advances in drug development have resulted in simplified treatments that are well-tolerated,...
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