Article
Ombitasvir, Paritaprevir, Ritonavir, and Dasabuvir Mini-Tabs Plus Ribavirin for Children Aged 3-11 Years with Hepatitis C Genotype 1a.
Advances in therapy - 1 Jul 2020
Rosenthal Philip, Narkewicz Michael R, Yao Betty B, Jolley Christopher D, Lobritto Steven J, Wen Jessica, Molleston Jean P, Hsu Evelyn K, Jonas Maureen M, Zha Jiuhong, Liu Li, Leung Daniel H
Abstract excerpt
INTRODUCTION: To assess the safety, efficacy, and pharmacokinetics of mini-tablet formulations of ombitasvir (OBV), paritaprevir (PTV), ritonavir, and dasabuvir (DSV) with or without ribavirin for 12 weeks in children infected with chronic hepatitis C virus (HCV) genotype (GT) 1. METHODS: This is an ongoing, open-label, Phase 2/3 study in children 3-11 years old infected with HCV GT1 who were HCV treatment-naïve...
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