Parkinson's Disease Risk Variant rs9638616 is Non-Specifically Associated with Altered Brain Structure and Function.

doi:10.3233/JPD-230455

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Article

Parkinson's Disease Risk Variant rs9638616 is Non-Specifically Associated with Altered Brain Structure and Function.

Journal of Parkinson's disease - 1 Jan 2024

Welton Thomas, Teo Thomas Wei Jun, Chan Ling Ling, Tan Eng-King, Tan Louis Chew Seng

Abstract excerpt

Background: A genome-wide association study (GWAS) variant associated with Parkinson's disease (PD) risk in Asians, rs9638616, was recently reported, and maps to WBSCR17/GALNT17, which is involved in synaptic transmission and neurite development. Objective: To test the association of the rs9638616 T allele with imaging-derived measures of brain microstructure and function. Methods: We analyzed 3-Tesla MRI and...

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PMID: 38640170
DOI: 10.3233/JPD-230455
PMCID: PMC11191537

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GALNT17

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