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The relationship between epigenetic age and the hallmarks of aging in human cells

16 May 2022

Abstract excerpt

Abstract Epigenetic clocks are mathematically derived age estimators that are based on combinations of methylation values that change with age at specific CpGs in the genome. These clocks are widely used to measure the age of tissues and cells 1,2 . The discrepancy between epigenetic age (EpiAge), as estimated by these clocks, and chronological age is referred to as EpiAge acceleration. Epidemiological studies...

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PMID: 37034474
DOI: 10.1038/s43587-022-00220-0

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