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Article

Causal effects of neuroticism on postpartum depression: a bidirectional mendelian randomization study.

Archives of women's mental health - 1 Oct 2024

Hu Qianying, Chen Jianhua, Ma Jingjing, Li Yuting, Xu Yifeng, Yue Chaoyan, Cong Enzhao

Abstract excerpt

PURPOSE: Postpartum depression (PPD) brings adverse and serious consequences to both new parents and newborns. Neuroticism affects PPD, which remains controversial for confounding factors and reverse causality in cross-sectional research. Therefore, mendelian randomization (MR) study has been adopted to investigate their causal relationship. METHODS: This study utilized large-scale genome-wide association study...

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Neuroticism
Causality
Depression, Postpartum
Genome-Wide Association Study
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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Identifiers

PMID: 38634868
DOI: 10.1007/s00737-024-01466-w
PMCID: PMC11405473

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