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Article

Genetic susceptibility of urolithiasis: comprehensive results from genome-wide analysis.

World journal of urology - 12 Apr 2024

Lin Lede, Ma Yucheng, Li Zhen, Liu Linhu, Hu Qibo, Zhou Liang

Abstract excerpt

BACKGROUND: The pathogenesis of urolithiasis is multi-factorial and genetic factors have been shown to play a significant role in the development of urolithiasis. We tried to apply genome-wide Mendelian randomization (MR) analysis and figure out reliable gene susceptibility of urolithiasis from the largest samples to date in two independent genome-wide association studies (GWAS) database of European ancestry....

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Identifiers

PMID: 38607442
DOI: 10.1007/s00345-024-04937-y

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