Novel Risk Loci Identified in a Genome-Wide Association Study of Urolithiasis in a Japanese Population

Abstract excerpt

Significance Statement Although there is evidence that genetic factors may play a substantial role in the risk of urolithiasis, the genetic basis for this condition remains largely unidentified. Previous genome-wide association studies (GWAS) have identified only six gene loci as risk-related. In this work, the authors performed a GWAS using 11,130 cases and 187,639 controls from the Japanese population,...

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