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CDK7 in breast cancer: mechanisms of action and therapeutic potential

11 Apr 2024

Abstract excerpt

Cyclin-dependent kinase 7 (CDK7) serves as a pivotal regulator in orchestrating cellular cycle dynamics and gene transcriptional activity. Elevated expression levels of CDK7 have been ubiquitously documented across a spectrum of malignancies and have been concomitantly correlated with adverse clinical outcomes. This review delineates the biological roles of CDK7 and explicates the molecular pathways through which...

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PMID: 38605321
DOI: 10.1186/s12964-024-01577-y

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