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Article

Effect of smoking-related features and 731 immune cell phenotypes on esophageal cancer: a two-sample and mediated Mendelian randomized study.

Frontiers in immunology - 1 Jan 2024

Yang Kaiqi, Li Shaoya, Ding Yuchen, Meng Xiaodie, Zhang Changhao, Sun Xiujing

Abstract excerpt

Introduction: Numerous observational studies have indicated that smoking is a substantial risk factor for esophageal cancer. However, there is a shortage of research that delves into the specific causal relationship and potential mediators between the two. Our study aims to validate the correlation between smoking-related traits and esophageal cancer while exploring the possible mediating effects of immune...

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Esophageal Cancer Research and Treatment
Esophageal Neoplasms
Genetic Associations and Epidemiology
Immunologic Factors
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Reproducibility of Results

Tobacco Smoking

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Identifiers

PMID: 38601154
DOI: 10.3389/fimmu.2024.1336817
PMCID: PMC11004242

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