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Investigation of HLA susceptibility alleles and genotypes with hematological disease among Chinese Han population.

PloS one - 1 Jan 2024

Li Ye-Mo, Li Yu-Xia, Li Dai-Yang, Zhou Ying, An Lin, Yuan Zhi-Yang, Du Ke-Ming, Zheng Zhong-Zheng

Abstract excerpt

Several genes involved in the pathogenesis have been identified, with the human leukocyte antigen (HLA) system playing an essential role. However, the relationship between HLA and a cluster of hematological diseases has received little attention in China. Blood samples (n = 123913) from 43568 patients and 80345 individuals without known pathology were genotyped for HLA class I and II using sequencing-based...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38593173
DOI: 10.1371/journal.pone.0281698
PMCID: PMC11003630

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