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Article

Association between polymorphism in the MTHFR gene and encephaloduroarteriosynangiosis-induced collateral circulation formation.

Journal of neurosurgery - 1 Oct 2024

Gao Gan, Bao Xiang-Yang, Wang Qian-Nan, Wang Xiao-Peng, Hao Fang-Bin, Liu Si-Meng, Wang Min-Jie, Guo Qing-Bao, Li Jing-Jie, Duan Lian

Abstract excerpt

OBJECTIVE: This study aimed to investigate whether high homocysteine (Hcy) levels associated with the MTHFR gene influence the formation of the collateral vascular network in patients with moyamoya disease (MMD) after encephaloduroarteriosynangiosis (EDAS) by influencing the number of endothelial progenitor cells (EPCs) in peripheral blood. METHODS: A total of 118 Chinese patients with bilateral primary MMD were...

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Source

Identifiers

PMID: 38579348
DOI: 10.3171/2024.1.JNS232121

Genes

MTHFR
MMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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