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Article

The roles of methylenetetrahydrofolate reductase 677C>T and 1298A>C polymorphisms in moyamoya disease patients.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery - 1 Oct 2014

Park Young Seok, Jeon Young Joo, Kim Hyun Seok, Han In Bo, Choi Joong-Uhn, Kim Dong-Seok, Kim Nam Keun

Abstract excerpt

PURPOSE: The methylenetetrahydrofolate reductase (MTHFR) 677C>T and 1298A>C polymorphisms, which are associated with hyperhomocysteinemia and nitric oxide (NO) deficiency (which is related to atherothrombosis and cerebral ischemia), have not been studied in moyamoya disease. A case-control study was performed to investigate whether the MTHFR 677C>T and 1298A>C polymorphisms contribute to moyamoya disease (MMD)....

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Source

Identifiers

PMID: 25098357
DOI: 10.1007/s00381-014-2495-3

Genes

MTHFR
MMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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