Article
Novel Susceptibility Loci for Moyamoya Disease Revealed by a Genome-Wide Association Study.
Stroke - 1 Jan 2018
Duan Lian, Wei Ling, Tian Yanghua, Zhang Zhengshan, Hu Panpan, Wei Qiang, Liu Sugang, Zhang Jun, Wang Yuyang, Li Desheng, Yang Weizhong, Zong Rui, Xian Peng, Han Cong, Bao Xiangyang, Zhao Feng, Feng Jie, Liu Wei, Cao Wuchun, Zhou Guoping, Zhu Chunyan, Yu Fengqiong, Yang Weimin, Meng Yu, Wang Jingye, Chen Xianwen, Wang Yu, Shen Bing, Zhao Bing, Wan Jinghai, Zhang Fengyu, Zhao Gang, Xu Aimin, Zhang Xuejun, Liu Jianjun, Zuo Xianbo, Wang Kai
Abstract excerpt
BACKGROUND AND PURPOSE: Moyamoya disease (MMD) is a rare cerebral vasculopathy characterized by bilateral internal carotid artery stenosis and often leads to stroke in children or young adults. Although familial inheritance is well recognized, the genetic basis of MMD remains poorly understood. METHODS: A 2-stage genome-wide association study was conducted involving 1492 cases and 5084 controls. In the discovery...
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