Moyamoya Disease: Physiological Mechanisms and Treatment Approaches

Abstract excerpt

Moyamoya disease (MMD) is a rare, progressive cerebrovascular disorder marked by stenosis of the terminal internal carotid arteries and the formation of fragile collateral vessels, leading to reduced cerebral perfusion and heightened risks of ischemic and hemorrhagic strokes. Its pathophysiology involves endothelial dysfunction, aberrant angiogenesis, and genetic mutations, notably in the RNF213 gene. This paper e...

Topics

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• Genetic Predisposition to Disease
• Moyamoya Disease
• Moyamoya disease diagnosis and treatment
• Phenotype
• Platelet Aggregation Inhibitors
• Predictive Value of Tests
• Risk Factors
• Treatment Outcome

Identifiers and source

Literature Corpus work

d270f205-a260-51ba-91e8-057c1d23b0a5

DOI

10.20944/preprints202504.1113.v1