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Article

Multidimensional data analysis revealed thyroiditis-associated TCF19 SNP rs2073724 as a highly ranked protective variant in thyroid cancer.

Aging - 4 Apr 2024

Ruan Xianhui, Liu Yu, Wu Shuping, Fu Guiming, Tao Mei, Huang Yue, Li Dapeng, Wei Songfeng, Gao Ming, Guo Shicheng, Ning Junya, Zheng Xiangqian

Abstract excerpt

BACKGROUND: Thyroid cancer represents the most prevalent malignant endocrine tumour, with rising incidence worldwide and high mortality rates among patients exhibiting dedifferentiation and metastasis. Effective biomarkers and therapeutic interventions are warranted in aggressive thyroid malignancies. The transcription factor 19 (TCF19) gene has been implicated in conferring a malignant phenotype in cancers....

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Share to Cell Line, Tumor
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Polymorphism, Single Nucleotide

Share to Thyroid Neoplasms

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Identifiers

PMID: 38579171
DOI: 10.18632/aging.205718
PMCID: PMC11042956

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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