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Article

Regulation of Keratocyte Phenotype and Cell Behavior by Substrate Stiffness.

ACS biomaterials science & engineering - 14 Sept 2020

Chen Jialin, Backman Ludvig J, Zhang Wei, Ling Chen, Danielson Patrik

Abstract excerpt

Corneal tissue engineering is an alternative way to solve the problem of lack of corneal donor tissue in corneal transplantation. Keratocytes with a normal phenotype and function in tissue-engineered cornea would be critical for corneal regeneration. Although the role of extracellular/substrate material stiffness is well-known for the regulation of the cell phenotype and cell behavior in many different cell...

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Identifiers

PMID: 33455266
DOI: 10.1021/acsbiomaterials.0c00510

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