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Single‐cell transcriptome analysis reveals keratinocyte subpopulations contributing to psoriasis in corneum and granular layer

26 Jan 2024

Abstract excerpt

Abstract Background Psoriasis is a chronic, inflammatory skin disease that is common and relapses easily. While the importance of keratinocyte proliferation in psoriasis development is well‐documented, the specific functional subpopulations of epidermal keratinocytes associated with this disease remain enigmatic. Materials and Methods Therefore, in our analysis of single‐cell transcriptome data from both normal...

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PMID: 38279596
DOI: 10.1111/srt.13572

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