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Article

Clinicopathological features and clinical outcomes associated with TP53 and BRAFNon-V600 mutations in cutaneous melanoma patients.

Cancer - 15 Apr 2017

Kim Dae Won, Haydu Lauren E, Joon Aron Y, Bassett Roland L, Siroy Alan E, Tetzlaff Michael T, Routbort Mark J, Amaria Rodabe N, Wargo Jennifer A, McQuade Jennifer L, Kemnade Jan, Hwu Patrick, Woodman Scott E, Roszik Jason, Kim Kevin B, Gershenwald Jeffrey E, Lazar Alexander J, Davies Michael A

Abstract excerpt

BACKGROUND: BRAFV600 , NRAS, TP53, and BRAFNon-V600 are among the most common mutations detected in non-acral cutaneous melanoma patients. Although several studies have identified clinical and pathological features associated with BRAFV600 and NRAS mutations, limited data are available regarding the correlates and significance of TP53 and BRAFNon-V600 mutations. METHODS: This study analyzed the patient...

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Source

Open in PubMed Open full text

Identifiers

PMID: 27911979
DOI: 10.1002/cncr.30463
PMCID: PMC5384865

Genes

NRAS
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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