Article
Association between novel genetic variants of Notch signaling pathway genes and survival of hepatitis B virus-related hepatocellular carcinoma.
Cancer medicine - 1 Apr 2024
Qin Liming, Qiu Moqin, Lin Qiuling, Jiang Binbin, Zhan Shicheng, Wei Xueyan, Wei Junjie, Liu Yingchun, Wen Qiuping, Chen Peiqin, Jiang Yanji, Zhou Zihan, Liang Xiumei, Cao Ji, Gong Yizhen, Wei Yuying, Wei Xiaoxia, Yu Hongping
Abstract excerpt
BACKGROUND: Although the Notch pathway plays an important role in formation and progression of hepatocellular carcinoma (HCC), few studies have reported the associations between functional genetic variants and the survival of hepatitis B virus (HBV)-related HCC. METHODS: In the present study, we performed multivariable Cox proportional hazard regression analysis to evaluate associations between 36,101 SNPs in 264...
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