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Article

Impact of Sonic Hedgehog-dependent sphenoid bone defect on craniofacial growth.

Clinical and experimental dental research - 1 Apr 2024

Guyodo Hélène, Rizzo Aurélie, Diab Farah, Noury Fanny, Mironov Svetlana, de Tayrac Marie, David Véronique, Odent Sylvie, Dubourg Christèle, Dupé Valérie

Abstract excerpt

OBJECTIVES: The main objective of this study was to evaluate how an apparently minor anomaly of the sphenoid bone, observed in a haploinsufficient mouse model for Sonic Hedgehog (Shh), affects the growth of the adult craniofacial region. This study aims to provide valuable information to orthodontists when making decisions regarding individuals carrying SHH mutation. MATERIALS AND METHODS: The skulls of...

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Identifiers

PMID: 38558491
DOI: 10.1002/cre2.861
PMCID: PMC10982674

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