Article
Retinol dehydrogenase 12 (RDH12) knock out may cause hyperuricemia phenotype in mice.
Biochemical and biophysical research communications - 21 May 2024
Bian Jiaxin, Chen Hongyu, Sun Junhui, Han Shuai, Qi Ming, Pan Qing
Abstract excerpt
Hyperuricemia is a chronic metabolic disease caused by purine metabolism disorder. And several gene loci and transporter proteins that associated with uric acid transport functions have been identified. Retinol Dehydrogenase 12 (RDH12), recognized for its role in safeguarding photoreceptors, and our study investigated the potential impact of Rdh12 mutations on other organs and diseases, particularly...
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