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Comprehensive Validation of Diagnostic Next-Generation Sequencing Panels for Acute Myeloid Leukemia Patients.

The Journal of molecular diagnostics : JMD - 1 Aug 2022

Wagner Ulrich, Wong Christine, Camenisch Ulrike, Zimmermann Kathrin, Rechsteiner Markus, Valtcheva Nadejda, Theocharides Alexandre, Widmer Corinne C, Manz Markus G, Moch Holger, Wild Peter J, Balabanov Stefan

Abstract excerpt

Next-generation sequencing has greatly advanced the molecular diagnostics of malignant hematological diseases and provides useful information for clinical decision making. Studies have shown that certain mutations are associated with prognosis and have a direct impact on treatment of affected patients. Therefore, reliable detection of pathogenic variants is critically important. Here, we compared four sequencing...

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High-Throughput Nucleotide Sequencing
Leukemia, Myeloid, Acute
Mutation
Myeloproliferative Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Reproducibility of Results

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PMID: 35718092
DOI: 10.1016/j.jmoldx.2022.05.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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