Article
Association between loss of hypercoagulable phenotype, clinical features and complement pathway consumption in COVID-19.
Frontiers in immunology - 1 Jan 2024
Kasugai Daisuke, Tanaka Taku, Suzuki Takako, Ito Yoshinori, Nishida Kazuki, Ozaki Masayuki, Kutsuna Takeo, Yokoyama Toshiki, Kaneko Hitoshi, Ogata Ryo, Matsui Ryohei, Goshima Takahiro, Hamada Hiroshi, Ishii Azusa, Kodama Yusuke, Jingushi Naruhiro, Ishikura Ken, Kamidani Ryo, Tada Masashi, Okada Hideshi, Yamamoto Takanori, Goto Yukari
Abstract excerpt
Background: Coronavirus disease 2019 (COVID-19) features a hypercoagulable state, but therapeutic anticoagulation effectiveness varies with disease severity. We aimed to evaluate the dynamics of the coagulation profile and its association with COVID-19 severity, outcomes, and biomarker trajectories. Methods: This multicenter, prospective, observational study included patients with COVID-19 requiring respiratory...
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