Article

Hypocoagulable Coagulation Profile and Endogenous Heparinoids Are Associated with Invasive Ventilation and Mortality in COVID-19

2021-03-15

Abstract excerpt

Background & Aims: A procoagulant state with pulmonary micro-thrombosis has been described in COVID-19, which contributes to pathophysiology of respiratory failure along with diffuse alveolar damage. Cytokine storm and systemic inflammation in COVID-19 generates endogenous heparinoids from the endothelium which leads to secondary organ failures. We prospectively studied the dynamic association of the coagulation...

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Literature Corpus work: 8b0c8d0c-d01b-52db-ab4b-ff8ab9f8c364
DOI: 10.2139/ssrn.3802514

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