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Article

Absence of association between Pfnfs1 mutation and in vitro susceptibility to lumefantrine in Plasmodium falciparum.

International journal for parasitology. Drugs and drug resistance - 1 Apr 2024

Zeng Weilin, Zhao Wei, Wei Hao, Qin Yucheng, Xiang Zheng, Wu Yanrui, Chen Xi, Zhang Yanmei, Zhao Hui, Duan Mengxi, Zhu Wenya, Sun Kemin, Wu Yiman, Liang Tao, Mou Ye, Liu Cheng, Tang Xiuya, Huang Yaming, Cui Liwang, Yang Zhaoqing

Abstract excerpt

Artemether-lumefantrine (AL) is the most widely used antimalarial drug for treating uncomplicated falciparum malaria. This study evaluated whether the K65Q mutation in the Plasmodium falciparum cysteine desulfurase IscS (Pfnfs1) gene was associated with alternated susceptibility to lumefantrine using clinical parasite samples from Ghana and the China-Myanmar border area. Parasite isolates from the China-Myanmar...

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Identifiers

PMID: 38520842
DOI: 10.1016/j.ijpddr.2024.100532
PMCID: PMC10979268

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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