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Article

Genomic structure of the horse major histocompatibility complex class II region resolved using PacBio long-read sequencing technology.

Scientific reports - 31 Mar 2017

Viļuma Agnese, Mikko Sofia, Hahn Daniela, Skow Loren, Andersson Göran, Bergström Tomas F

Abstract excerpt

The mammalian Major Histocompatibility Complex (MHC) region contains several gene families characterized by highly polymorphic loci with extensive nucleotide diversity, copy number variation of paralogous genes, and long repetitive sequences. This structural complexity has made it difficult to construct a reliable reference sequence of the horse MHC region. In this study, we used long-read single molecule,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28361880
DOI: 10.1038/srep45518
PMCID: PMC5374520

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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