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Identification of potential biomarkers for aging diagnosis of mesenchymal stem cells derived from the aged donors

22 Mar 2024

Abstract excerpt

BACKGROUND: The clinical application of human bone-marrow derived mesenchymal stem cells (MSCs) for the treatment of refractory diseases has achieved remarkable results. However, there is a need for a systematic evaluation of the quality and safety of MSCs sourced from donors. In this study, we sought to assess one potential factor that might impact quality, namely the age of the donor. METHODS: We downloaded two...

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PMID: 38520027
DOI: 10.1186/s13287-024-03689-1

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