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A Mesenchymal Stromal Cell Gene Signature for Donor Age

23 Aug 2012

Abstract excerpt

Human aging is associated with loss of function and regenerative capacity. Human bone marrow derived mesenchymal stromal cells (hMSCs) are involved in tissue regeneration, evidenced by their capacity to differentiate into several lineages and therefore are considered the golden standard for cell-based regeneration therapy. Tissue maintenance and regeneration is dependent on stem cells and declines with age and...

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PMID: 22927939
DOI: 10.1371/journal.pone.0042908

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