Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

STING is significantly increased in high-grade glioma with high risk of recurrence.

Oncoimmunology - 1 Jan 2024

Zhong Meishi, Long Manmei, Han Chenjie, Ji Saiyan, Yang Qingyuan

Abstract excerpt

In this study, we aimed to comprehensively characterize the potential relationships among the frequently mutated genes, well-known homologous recombination repair (HRR) proteins, and immune proteins in glioma from a clinical perspective. A total of 126 surgical tissues from patients initially diagnosed with glioma were included. The genetic alterations were tested using the targeted next-generation sequencing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to ATRX gene
Share to RAD51 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glioma

Share to Membrane Proteins

Share to Mutation

Share to Neoplasm Recurrence, Local

Share to Recurrence

Source

Open in PubMed Open full text

Identifiers

PMID: 38516268
DOI: 10.1080/2162402X.2024.2327682
PMCID: PMC10956623

Genes

ATRX
IDH1
RAD51
TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

STING is significantly increased in high-grade glioma with high risk of recurrence.PMID 38516268Read ↗

A Prognostic DNA Damage Repair Genes Signature and Its Impact on Immune Cell Infiltration in GliomaSemantic proximity Read ↗

A novel DNA damage and repair-related gene signature to improve predictive capacity of overall survival for patients with gliomas.Semantic proximity Read ↗

Interferon gamma-related gene signature based on anti-tumor immunity predicts glioma patient prognosisSemantic proximity Read ↗

Novel, clinically relevant genomic patterns identified by comprehensive genomic profiling in ATRX-deficient IDH-wildtype adult high-grade gliomas.Semantic proximity Read ↗

Histone deacetylase 6 acts upstream of DNA damage response activation to support the survival of glioblastoma cellsSemantic proximity Read ↗

The Role of ATRX in Glioma BiologySemantic proximity Read ↗

Omics-based integrated analysis identified ATRX as a biomarker associated with glioma diagnosis and prognosisSemantic proximity Read ↗

IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage responseSemantic proximity Read ↗

Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas.Semantic proximity Read ↗

DNA repair genes in astrocytoma tumorigenesis, progression and therapy resistanceSemantic proximity Read ↗

Molecular Study of Long-Term Survivors of Glioblastoma by Gene-Targeted Next-Generation Sequencing.Semantic proximity Read ↗

HAT1 regulates the immune microenvironment and promotes the malignant pathology of lower-grade gliomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.