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Article

Knowledge-Based Therapeutics for Tricarboxylic Acid (TCA) Cycle-Deficient Cancers.

Cold Spring Harbor perspectives in medicine - 3 Sept 2024

Peled Daniel, Casey Ruth, Gottlieb Eyal

Abstract excerpt

With the foundation pre-laid, research in the new millennium has readily excavated and expanded upon the architectural framework laid out by Otto Warburg's seminal work in a new wave of "westward expansion," ever widening our understanding of cancer metabolism beyond the telescopic vision seen over a century ago. On this path, the unique circuitry of the cancer metabolic program has been elucidated, illuminating...

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Identifiers

PMID: 38503501
DOI: 10.1101/cshperspect.a041536
PMCID: PMC11368189

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