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Article

Developmental Dopaminergic Signaling Modulates Neural Circuit Formation and Contributes to Autism Spectrum Disorder-Related Phenotypes.

The American journal of pathology - 1 Jun 2024

Lu Xiaojuan, Song Yixing, Wang Jiaqi, Cai Yunyun, Peng Siwan, Lin Jiaqi, Lai Biqin, Sun Junjie, Liu Tianqing, Chen Gang, Xing Lingyan

Abstract excerpt

Autism spectrum disorder (ASD) is a prevalent neurodevelopmental disorder with a complex etiology. Recent evidence suggests that dopamine plays a crucial role in neural development. However, whether and how disrupted dopaminergic signaling during development contributes to ASD remains unknown. In this study, human brain RNA sequencing transcriptome analysis revealed a significant correlation between changes in...

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Identifiers

PMID: 38492733
DOI: 10.1016/j.ajpath.2024.02.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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