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Article

Evidence for genetic causality between iron homeostasis and Parkinson's disease: A two-sample Mendelian randomization study.

Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) - 1 Jul 2024

Chen Hong, Wang Xie, Chang Ze, Zhang Juan, Xie Daojun

Abstract excerpt

BACKGROUND: Parkinson's disease (PD) is a degenerative disease of the central nervous system, and its specific etiology is still unclear. At present, it is believed that the main pathological basis is the reduction of dopamine concentration in the brain striatum. Although many previous studies have believed that iron as an important nutrient element participates in the occurrence and development of PD, whether...

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PMID: 38484633
DOI: 10.1016/j.jtemb.2024.127430

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