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Diagnostic Model for Alzheimer’s Disease Based on PANoptosis-Related Genes

29 Dec 2023

Abstract excerpt

BACKGROUND: The pathophysiology of Alzheimer's disease (AD) involves the interplay of three different processes: pyroptosis, apoptosis, and necroptosis. OBJECTIVE: To explore role of PANoptosis, a novel pro-inflammatory programmed cell death pathway, in AD patients. METHODS: We performed a consensus clustering analysis to identify distinct transcriptional profiles in the samples using the R package...

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PMID: 38160361
DOI: 10.3233/jad-231103

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